MEDICATION	DOSAGES & INTERVALS OF ADMINISTRATION	ROUTE & FINAL DILUTION	DILUTION INSTRUCTIONS	STABILITY	RATE OF INFUSION & COMMENTS
PARALDEHYDE (Neo) Mechanism of action: Anticonvulsant; Sedative Unknown mechanism of action. 1 g/mL injection Ref: Last update: 2013-08-08	Seizures Refractory to Standard Anticonvulsants: Loading dose: 3 mL/kg/hr (150 mg/kg/hr) of a 5% solution in NS or D5W x 3 hours Maintenance dose: 0.4 mL/kg/hr (20 mg/kg/hr) of a 5% solution in NS or D5W PR: 0.3 mL/kg/dose (300 mg/kg) Q4 to 6H PRN. Dissolve dose in equal volume of mineral oil prior to administration. Irregularly absorbed by rectal route.	IV 50 mg/mL (0.05 g/mL) (5% solution) PR	For IV administration: Add 2.5 mL (2.5 grams) to 50 mL of NS or D5W to make a 5% solution.	IV tubing (and syringe if plastic) should be replaced every 4 hours. Syringe and tubing must be protected from light by wrapping.	Administration: Administer via syringe pump (glass syringe preferred). COMMENTS: Routine use discouraged except for treatment of status epilepticus resistant to initial therapy with phenobarbital, phenytoin, diazepam or lorazepam. Adverse Effects: pulmonary edema and hemorrhage, hypotension, local irritation, displacement of bilirubin from albumin. Contraindications: pulmonary or hepatic disease. Standard Prescription: paraldehyde 5% solution loading dose __mL/kg/hr (__mg/kg/hr) x __hours paraldehyde 5% solution maintenance dose __mL/kg/hr (__mg/kg/hr) paraldehyde__mL PR Q__H PRN (__mL/kg/dose)