CELECOXIB
(Celebrex)Standard Prescription
celecoxib __mg PO__(frequency)
Dosages
Juvenile Idiopathic Arthritis (JIA):
Children >2 years old:
10 to 25 kg: 50 mg PO BID
>25 kg: 100 mg PO BID
Adults:
100 - 200 mg/dose PO daily or BID.
Maximum: 400 mg/24 hours
Children >2 years old:
10 to 25 kg: 50 mg PO BID
>25 kg: 100 mg PO BID
Adults:
100 - 200 mg/dose PO daily or BID.
Maximum: 400 mg/24 hours
Mechanism of Action
A COX-2 selective, non-steroidal anti-inflammatory drug (NSAID).
Forms Supplied
capsule: 100 mg, 200 mg
suspension (BCCH):
10 mg/mL
10 mg/mL
Comments
May increase serum levels of digoxin, methotrexate and lithium. May decrease the antiplatelet effects of ASA.
Note: concomitant use of methotrexate and NSAID is a standard of care for treating JIA.
Minimal platelet effect compared to other NSAIDs.
See Health Canada warning (2006) for cardiovascular risks.
References
44, 156
Last Edited
2021-11-13 05:08:37