BREVICON

(ethinyl estradiol and norethindrone)

Standard Prescription

Prevention of menstruation:
Brevicon 1 tablet PO daily

Acute abnormal uterine bleed:
Brevicon 1 tablet PO__(frequency) x __ days

Dosages

Prevention of menstrual bleeds in post-menarchal patients:
one tablet PO daily (continuous)

Acute abnormal uterine bleeding: (including break-through bleeding with leuprolide in oncology patients):
1 tablet TID-QID until cessation of bleeding then taper as tolerated to maintain control of bleeding

Mechanism of Action

Hormone; Oral contraceptive

Forms Supplied

tablet: 35 mcg ethinyl estradiol and 1 mg norethindrone

Comments

Contains higher estrogen content than other oral contraceptives.

Consider concurrent administration of an anti-emetic.

Not recommended if receiving bone marrow or stem cell transplant due to risk of hyperbilirubinemia and hepatic veno-occlusive disease.

May be safely administered with short courses (2-5 days) of tranexamic acid.

May be used for emergency contraception if levonorgestrel (Plan B) is unavailable. Levonorgestrel preferred due to effectiveness and safety profile.

References

143, 153, 413, 658, 661

Last Edited

2022-06-08 22:40:15