NEOSTIGMINE
(Prostigmin)Standard Prescription
Diagnosis: neostigmine__mg IM x 1 dose
Treatment: neostigmine__mg IM/IV/SC Q__H PRN (__mg/kg/dose)
Treatment: neostigmine__mg IM/IV/SC Q__H PRN (__mg/kg/dose)
Dosages
Myasthenia Gravis:
Diagnosis (use with atropine) *
Children: 0.025-0.04 mg/kg IM x 1.
Adults: 0.022 mg/kg IM x 1.
Treatment
Children: 0.01-0.04 mg/kg/dose IM/IV/SC Q2-4H PRN.
Adults: 0.5-2.5 mg/dose IM/IV/SC Q1-3H PRN to maximum 10 mg/24 hr. Mechanism of Action
Acetylcholinesterase inhibitor
Forms Supplied
Injection: 0.5 mg/mL
Comments
Dose must be titrated to avoid excessive cholinergic effects.
* For diagnosis of Myasthenia Gravis, give atropine 0.011 mg/kg IV with, or IM 30 minutes before neostigmine.
Antidote for neostigmine is atropine 0.01-0.04 mg/kg/dose.
Contraindicated in GI and urinary obstruction.
Caution in patients with asthma.
* For diagnosis of Myasthenia Gravis, give atropine 0.011 mg/kg IV with, or IM 30 minutes before neostigmine.
Antidote for neostigmine is atropine 0.01-0.04 mg/kg/dose.
Contraindicated in GI and urinary obstruction.
Caution in patients with asthma.
References
44
Last Edited
2023-01-12 06:07:24