NAPROXEN
(Naprosyn)Standard Prescription
Children:
naproxen__mg PO{PR}__(frequency) (__mg/kg/dose) or (mg/kg/24hr)
Adults:
naproxen__mg PO__(frequency) (prn)
naproxen__mg PO{PR}__(frequency) (__mg/kg/dose) or (mg/kg/24hr)
Adults:
naproxen__mg PO__(frequency) (prn)
Dosages
Children >2 years:
Adults:
Analgesic:
Analgesic: 5-7 mg/kg/dose PO Q8-12H.
Anti-inflammatory (e.g. JIA): 5-10 mg/kg/dose PO div. BID, Max 20 mg/kg/24 hr.
Maximum: 1000 mg/24 hr.
Adults:
Analgesic:
250-500 mg/dose PO BID.
Dysmenorrhea:
500 mg x 1, then 250 mg PO Q6-8H PRN.
Maximum: 1250 mg/24 hr.
Mechanism of Action
Non-steroidal anti-inflammatory drug (NSAID)
Forms Supplied
tablet: 125 mg, 250 mg
suspension: 25 mg/mL
375 mg and 500 mg tablets are available but not stocked at BCCH
Manufacture of suppositories was discontinued in 2017.
Comments
Naproxen is the most common first-line agent for treating JIA
May increase serum levels of digoxin, methotrexate and lithium. May decrease the antiplatelet effects of ASA.
Note: concomitant use of methotrexate and NSAID is a standard of care for treating JIA.
May cause photosensitive vesicular rash in fair skinned children (pseudoporphyria).
May increase serum levels of digoxin, methotrexate and lithium. May decrease the antiplatelet effects of ASA.
Note: concomitant use of methotrexate and NSAID is a standard of care for treating JIA.
May cause photosensitive vesicular rash in fair skinned children (pseudoporphyria).
References
44, 138, 156
Last Edited
2022-03-01 00:13:07