MAGNESIUM SULFATE
Standard Prescription
magnesium sulfate __mg IM/IV Q__H x __ doses (__mg/kg/dose)
magnesium sulfate __mg IV over 20 minutes x 1 dose (__mg/kg/dose)
magnesium sulfate __mg IV over 20 minutes x 1 dose (__mg/kg/dose)
Dosages
Hypomagnesemia or Hypocalcemia:
25-50 mg magnesium sulfate/kg/dose
(2.5-5 mg elemental magnesium/kg/dose) IM/IV every 6 hours x 2-3 doses PRN.
Maximum: 2 g magnesium sulfate/dose (200 mg elemental magnesium/dose)
Daily Maintenance:
30-60 mg magnesium sulfate/kg/24 hr (3-6 mg elemental magnesium/kg/24 hr IV) Oral dosing will be found under "Magnesium supplements, oral"
Severe acute asthma:
25-50 mg magnesium sulfate/kg (2.5-5 mg elemental magnesium/kg/dose) IV over 20 minutes x 1 dose
Maximum: 2 g magnesium sulfate/dose (200 mg elemental magnesium/dose)
25-50 mg magnesium sulfate/kg/dose
(2.5-5 mg elemental magnesium/kg/dose) IM/IV every 6 hours x 2-3 doses PRN.
Maximum: 2 g magnesium sulfate/dose (200 mg elemental magnesium/dose)
Daily Maintenance:
30-60 mg magnesium sulfate/kg/24 hr (3-6 mg elemental magnesium/kg/24 hr IV) Oral dosing will be found under "Magnesium supplements, oral"
Severe acute asthma:
25-50 mg magnesium sulfate/kg (2.5-5 mg elemental magnesium/kg/dose) IV over 20 minutes x 1 dose
Maximum: 2 g magnesium sulfate/dose (200 mg elemental magnesium/dose)
Mechanism of Action
Electrolyte
Forms Supplied
Injection: 50% (500 mg/mL) - 10 mL
Standard concentrations for Critical Care:
PICU: 10 mg/ml, 100 mg/mL, 200 mg/mL
Standard concentrations for Critical Care:
PICU: 10 mg/ml, 100 mg/mL, 200 mg/mL
Comments
Each mL contains 500 mg magnesium sulfate = 50 mg elemental Mg = 2 mmol (4 mEq)
Rapid IV administration may cause arrhythmias, hypotension, respiratory and CNS depression. Maximum infusion rate: 125 mg MgSO4/kg/hr (0.5 mmol/kg/hr)
Patients who waste magnesium in urine or stool may require much larger doses, but the adverse effect of diarrhea from oral magnesium may be dose limiting
When using IV doses, monitor serum magnesium level daily
Use with caution in renal failure
Rapid IV administration may cause arrhythmias, hypotension, respiratory and CNS depression. Maximum infusion rate: 125 mg MgSO4/kg/hr (0.5 mmol/kg/hr)
Patients who waste magnesium in urine or stool may require much larger doses, but the adverse effect of diarrhea from oral magnesium may be dose limiting
When using IV doses, monitor serum magnesium level daily
Use with caution in renal failure
References
44, 54, 135
Last Edited
2022-04-04 19:43:32