CYPROHEPTADINE
(Periactin)Standard Prescription
cyproheptadine__mg PO__(frequency) (__mg/kg/day)
Dosages
Cyclic Vomiting Syndrome (CVS) Prophylaxis:
0.125-0.25 mg/kg/dose PO BID or TID (Max 0.5 mg/kg/day)
Appetite Stimulant:
0.125 mg/kg/dose PO div BID
0.125-0.25 mg/kg/dose PO BID or TID (Max 0.5 mg/kg/day)
Appetite Stimulant:
0.125 mg/kg/dose PO div BID
Mechanism of Action
Antihistamine
Forms Supplied
Tablet: 4 mg
Comments
CVS prophylactic dosing is for children < 5 yrs old, use amitriptyline for >5 yrs old.
anticholinergic side effects including increased appetite, weight gain, sedation.
paradoxical hyperexcitability may occur in some children.
For use as an appetite stimulant, a dosing cycle of 13 weeks on therapy, followed by 1 week off therapy may enhance efficacy.
anticholinergic side effects including increased appetite, weight gain, sedation.
paradoxical hyperexcitability may occur in some children.
For use as an appetite stimulant, a dosing cycle of 13 weeks on therapy, followed by 1 week off therapy may enhance efficacy.
References
1, 21, 420
Last Edited
2019-01-16 06:01:13