DRUG	SUPPLIED	DOSE	COMMENTS
THIAMINE (Paeds) (Vitamin B1) Mechanism of action: Vitamin B1 Ref: 44, 62, 259, 649 Last update: 2022-09-12	tablet: 50 mg liquid (BCCH): 100 mg/mL injection: 100 mg/mL	Patients at risk of Thiamine deficiency: 0.35-0.5mg/kg/day PO daily Patients at risk of Refeeding Syndrome: Child: 2 mg/kg PO/IV/IM daily. Max: 100-200 mg/day Adult: 100 mg PO/IV/IM daily *continue for 5-7 days, or longer if severe starvation, chronic alcoholism or other high risk of deficiency +/- signs of thiamine deficiency Severe Deficiency, treatment: Infant: 25-50 mg IV x 1 dose, then 10 mg IM daily x 1 week, then 3-5 mg PO daily x at least 6 weeks Child: 10 mg IM/IV daily x 1 week (if critically ill), then 3-5 mg PO daily x at least 6 weeks Adolescents: 100 mg IV/IM daily x up to 7 days (if critically ill), then 10 mg PO once daily	Parenteral administration is preferred in critically ill patients. Higher doses may be required in metabolic disorders such as Maple Syrup disease. Start thiamine prior to initiating feeding or dextrose-containing IV fluid. Standard Prescription: thiamine__mg PO{IM/IV}__(frequency)