DRUG SUPPLIED DOSE COMMENTS
HYDROCHLOROTHIAZIDE (Paeds)
(HydroDiuril, HCTZ)

Mechanism of action:

Thiazide diuretic



Ref: 44, 192



Last update: 2019-03-12
tablet: 25 mg, 50 mg
suspension (BCCH): 5 mg/mL
Infant < 6 mo.:
1-2 mg/kg/dose PO BID to max. 37.5 mg/day

Infant > 6 mo. & child:
1 mg/kg/dose PO BID to max 100 mg/day (child)

Adult:
25-100 mg/24 hr PO daily or divided BID to max. 200 mg/day
Monitor serum electrolytes; May cause hyponatremia, hypokalemia, hypomagnesemia.

Loss of efficacy at GFR<40 mL/min; avoid use if GFR <10 mL/min

Onset within 2 hrs; duration 6-12 hr


Standard Prescription:

hydrochlorothiazide__mg PO__(frequency) (__mg/kg/24hr)